Diabetic Skin Ulcers: Causes, Treatment, and Prevention

A diabetic skin ulcer is an open sore or wound that struggles to heal, a significant health issue for individuals with diabetes. These ulcers commonly form on the feet and legs. Due to factors associated with diabetes, a minor scrape can fail to heal properly and progress into a persistent wound. This slow healing process makes ulcers a serious complication, as they can become infected and lead to severe health problems if not addressed promptly.

Underlying Causes and Risk Factors

The development of diabetic ulcers is driven by a combination of factors that compromise the body’s natural healing capabilities. One major contributor is diabetic neuropathy, nerve damage resulting from prolonged high blood sugar. This condition causes a loss of sensation, particularly in the feet, meaning a person might not feel a small cut or pressure sore. Without the signal of pain, an injury can go unnoticed and worsen over time.

Poor blood circulation, often due to peripheral artery disease (PAD), is another foundational cause. Diabetes can damage blood vessels, narrowing the arteries and reducing blood flow to the extremities. This diminished circulation impairs the body’s ability to deliver the oxygen and nutrients necessary for tissue repair and wound healing.

Sustained high blood sugar also weakens the immune system, making it harder to fight off infection, and can stiffen tissues, further impeding healing. Other factors that elevate risk include foot deformities such as bunions or Charcot foot, which create abnormal pressure points. A history of previous ulcers also increases the chances of recurrence.

Identification and Staging

Recognizing a diabetic ulcer early is a large part of preventing serious complications. One of the most common indicators is drainage from a sore on the foot, which may stain socks or shoes. Other symptoms include unusual swelling, localized redness, and a distinct odor, which often points to an underlying infection. Due to diabetic neuropathy, pain is often absent, so it cannot be relied upon as a warning sign.

These ulcers most frequently appear in high-pressure areas of the feet. Common locations include the bottom of the big toe, the balls of the feet, and the heels, as these spots bear the most weight. Daily inspection of the feet is therefore recommended for individuals with diabetes to catch any skin changes, like blisters or cuts, before they progress.

The progression of a diabetic ulcer can be understood through a staging system, which helps determine the wound’s severity. A simplified way to view this is by its depth. An ulcer may begin as a superficial red spot or a shallow sore. If it worsens, it can evolve into a deep crater that exposes underlying tissues, and in advanced stages, may reveal tendons or bone.

Medical Treatments and Management

The primary goals of treating a diabetic foot ulcer are to facilitate healing and prevent infection. A foundational treatment is “off-loading,” which involves relieving pressure from the affected area. This is often accomplished with specialized footwear, custom braces, casts, or a wheelchair to keep weight off the foot. Protecting the wound from pressure stops further tissue damage and supports healing.

Another standard procedure is debridement, the medical removal of dead or infected tissue from the wound bed. This process cleans the ulcer and stimulates the growth of healthy new tissue. Following debridement, specialized dressings are applied to keep the wound moist and protected, which accelerates healing. If an infection is present, a provider will likely prescribe antibiotics.

For ulcers that do not respond to conventional treatments, advanced therapies may be considered. Hyperbaric oxygen therapy involves breathing pure oxygen in a pressurized room to increase the oxygen supply to the wound. Surgical interventions might also be necessary, such as skin grafts to close the wound or vascular surgery to improve blood flow.

Prevention and Home Care

Preventing diabetic ulcers is centered on consistent self-care and diabetes management. The most effective strategy is maintaining stable blood glucose levels, as high blood sugar is a root cause of nerve and blood vessel damage. Careful monitoring and adherence to a prescribed diet, exercise, and medication plan can significantly lower this risk.

Daily foot care is another cornerstone of prevention. This includes:

  • Washing the feet with mild soap and warm water, then thoroughly drying them, especially between the toes.
  • Applying moisturizer to the tops and bottoms of the feet to prevent cracking, but avoiding the area between the toes.
  • Trimming toenails straight across to prevent ingrown toenails that can lead to injury and infection.
  • Wearing well-fitting, supportive shoes and avoiding materials that cause friction or pressure.

It is advisable to never walk barefoot to avoid cuts or scrapes that might go unnoticed. Regular examinations by a podiatrist or healthcare provider are also beneficial, as they can identify potential problems before they escalate into ulcers.

Serious Complications

If a diabetic ulcer is not treated effectively or becomes severely infected, it can lead to dangerous complications. An untreated open wound provides a gateway for bacteria, which can result in a serious skin infection known as cellulitis. This condition causes redness, swelling, and warmth in the affected area and can spread rapidly if not managed with antibiotics.

The infection can also penetrate deeper than the skin, reaching the bone and causing a condition called osteomyelitis. A bone infection is much more difficult to treat than a skin infection. It often requires long-term intravenous antibiotics or even surgical removal of the infected bone tissue.

In the most severe cases, persistent infection and lack of blood flow can lead to gangrene, which is the death of body tissue. When tissue dies, it cannot be saved, and the condition can spread, leading to systemic infection and sepsis. To stop the progression of the infection, amputation of the affected toe, foot, or part of the leg may become the only viable option.

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