Cloperastine is a medication primarily used to manage cough. It functions as a cough suppressant, helping to alleviate the discomfort associated with persistent coughing. This medication is available in different formulations, such as syrup and tablets, for oral administration.
Cloperastine Explained
Cloperastine is a non-opioid antitussive. It suppresses coughing without the addiction potential or respiratory depression associated with opioid-based drugs.
It treats non-productive, or dry, coughs that do not produce phlegm or mucus. This includes coughs from common conditions like bronchitis, the common cold, or certain allergic reactions.
Cloperastine is widely used in several parts of the world, including Japan and some European countries, under brand names like Hustazol and Seki. It provides relief from irritating coughs that can significantly interfere with daily activities or sleep. The medication comes in forms such as oral tablets and syrup, making it accessible for different patient groups, including children over two years of age.
How Cloperastine Works
Cloperastine primarily acts on the central nervous system to suppress the cough reflex. It targets the cough center in the medulla oblongata, a part of the brain controlling involuntary functions like breathing and coughing. By inhibiting signals in this region, cloperastine effectively reduces the frequency and intensity of coughing episodes.
Unlike opioid cough suppressants, cloperastine achieves this effect without significantly depressing the respiratory center or posing an addiction risk. Beyond its central action, cloperastine also possesses mild antihistaminic and anticholinergic properties. These additional actions can help reduce irritation and inflammation in the respiratory tract, potentially decreasing mucus secretion and relaxing bronchial muscles, which further contributes to cough suppression.
Key Safety Information
Like all medications, cloperastine can cause side effects, though generally mild and temporary. Common side effects include drowsiness, dry mouth, and gastrointestinal discomfort such as nausea or stomach upset. Drowsiness is a frequently reported effect due to the medication’s action on the central nervous system, so caution is advised when performing tasks requiring alertness, such as driving or operating machinery. Dry mouth can often be managed by staying hydrated or using sugar-free gum.
Warnings and contraindications exist for cloperastine. The medication is generally not recommended for children younger than two years of age. Individuals with a known hypersensitivity or allergy to cloperastine or its components should not take it. Caution is also advised for patients with certain pre-existing conditions, including glaucoma, prostate hypertrophy (enlarged prostate), or severe liver dysfunction, as the medication’s mild anticholinergic effects could potentially worsen these conditions.
Pregnant or breastfeeding women should consult their healthcare provider before using cloperastine, as its safety in these populations has not been fully established. Interactions with other drugs can occur. Combining cloperastine with other central nervous system depressants, such as alcohol, sedatives, or certain antihistamines, can enhance drowsiness and other side effects. It is important to inform a healthcare provider about all medications, supplements, and herbal products being taken to avoid potential interactions.
Taking Cloperastine
Cloperastine is typically administered orally. The specific dosage and frequency depend on factors such as the patient’s age and the severity of their symptoms. For adults, a common dosage might involve taking 10 to 20 mg two to three times daily. Children’s dosages are usually lower and are determined based on their weight and age.
It is important to follow the precise dosage and administration guidelines provided by a healthcare professional or the product’s instructions. The medication can generally be taken with or without food. If a dose is missed, take it as soon as remembered, unless it is almost time for the next scheduled dose, in which case the missed dose should be skipped. Storage of cloperastine should ideally be at room temperature, away from direct light and moisture, and kept out of reach of children and pets.