Can Meloxicam Cause Canker Sores?

This article explores the potential link between meloxicam and canker sores, providing information to help you understand this topic.

What Meloxicam Is and Its Common Uses

Meloxicam is a medication classified as a nonsteroidal anti-inflammatory drug, commonly known as an NSAID. It functions by reducing certain substances in the body that contribute to pain, inflammation, and fever. Specifically, meloxicam works by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins, mediators of inflammation.

This medication is frequently prescribed to alleviate symptoms associated with various forms of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. Meloxicam is available in different forms, such as tablets and oral suspensions, and is typically taken once daily.

Canker Sores: An Overview

Canker sores, also known as aphthous ulcers, are small, shallow lesions that develop on the soft tissues inside the mouth, such as the cheeks, lips, tongue, or at the base of the gums. They typically appear as a white or yellowish center surrounded by a distinct red border. While generally not contagious, canker sores can be quite painful and may make eating and talking uncomfortable.

The precise cause of canker sores is often unclear, but several factors can trigger their development. Common triggers include minor injuries to the mouth, such as accidentally biting the cheek or trauma from dental work. Stress, consumption of acidic foods like citrus fruits, and certain nutritional deficiencies, particularly in vitamin B12, zinc, folic acid, or iron, are also linked to their occurrence. Hormonal changes, food sensitivities, and genetics can also play a role.

Connecting Meloxicam to Canker Sores

The direct causal link between meloxicam and canker sores is not among the most common or well-documented adverse reactions. While meloxicam, like other NSAIDs, can have various side effects, some sources list canker sores as a possible side effect.

The mechanism by which NSAIDs might contribute to oral ulcers is believed to be related to their impact on prostaglandin production. Prostaglandins play a protective role in maintaining the integrity of mucous membranes, including those in the mouth. By inhibiting prostaglandin synthesis, meloxicam may reduce this protective effect, potentially making the oral mucosa more susceptible to ulcer formation.

It is important to note that while a connection exists, canker sores are far more commonly triggered by other factors. If canker sores develop while taking meloxicam, it is often challenging to definitively attribute them solely to the medication without ruling out other prevalent causes.

Managing Canker Sores While on Meloxicam

If you experience canker sores while taking meloxicam, consulting a healthcare provider is an important first step before making any changes to your medication. They can help determine the likely cause of the sores and advise on the most appropriate course of action. Self-treating or discontinuing meloxicam without medical guidance is not recommended.

For symptomatic relief, several strategies can help manage the discomfort of canker sores. Over-the-counter topical treatments, such as gels or patches containing benzocaine or fluocinonide, can provide localized pain relief. Mouth rinses can also be beneficial; warm salt water rinses or solutions made with baking soda can help soothe the area. Some healthcare providers may recommend prescription mouth rinses containing dexamethasone to reduce inflammation or lidocaine for pain relief.

Avoiding foods that can irritate the sores, such as acidic, spicy, or abrasive items, is also advisable. Maintaining good oral hygiene by brushing gently with a soft-bristled toothbrush can prevent further irritation.

Seek medical attention if canker sores:
Are unusually large
Spread
Persist for more than two weeks
Cause extreme pain that interferes with eating or drinking
Are accompanied by other symptoms like fever

Your doctor might consider alternative medications or further investigations if a strong link between meloxicam and the canker sores is suspected.

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