Aripiprazole, known by brand names like Abilify or Aristada, is an atypical antipsychotic medication. It functions as a dopamine-serotonin system stabilizer, balancing these neurotransmitters in the brain. This article explores common user experiences with aripiprazole, including its reported benefits and potential drawbacks.
What Aripiprazole is Prescribed For
Aripiprazole is approved by the U.S. Food and Drug Administration (FDA) for treating several mental health conditions. It is prescribed for schizophrenia, a chronic mental disorder affecting how a person thinks, feels, and behaves. The medication also treats acute manic and mixed episodes associated with bipolar I disorder, a condition characterized by significant mood swings.
Additionally, aripiprazole serves as an adjunctive treatment for major depressive disorder (MDD) when antidepressants alone are insufficient. It is also indicated for managing irritability linked to autistic disorder, a developmental condition affecting communication and behavior.
Common Reported Positive Effects
Many individuals taking aripiprazole report a reduction in intrusive thoughts. Users frequently describe a newfound sense of emotional stability, leading to feeling less agitated.
Aripiprazole has also been noted to contribute to clearer thinking, improving focus and cognitive function. This often translates into an increased ability to engage in daily activities. Reports also include improved outlook and energy levels.
Common Reported Side Effects and Negative Experiences
Common side effects of aripiprazole include akathisia, characterized by an intense inner restlessness and a compelling urge to move constantly. This can manifest as an inability to sit still, fidgeting, or pacing. Other common issues include weight gain, drowsiness or fatigue, insomnia, nausea, vomiting, constipation, and blurred vision.
More serious concerns include specific FDA warnings. A black box warning highlights an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults. Another black box warning advises against its use in elderly patients with dementia-related psychosis, as it may increase the risk of death. Monitoring for signs of high blood sugar or diabetes and changes in cholesterol levels is also important.
A notable risk is the potential for impulse-control problems. Some individuals may develop new or worsened compulsive behaviors, such as compulsive gambling, uncontrolled shopping, binge eating, or hypersexuality. These urges can be intense and difficult to control. Any new or worsening urges or behaviors should be discussed with a healthcare provider immediately.
The Experience of Stopping Aripiprazole
Discontinuing aripiprazole requires careful medical supervision and should never be done abruptly, as this can lead to withdrawal or discontinuation symptoms. Healthcare professionals recommend a gradual tapering process to minimize potential adverse effects.
Users who have stopped aripiprazole report various discontinuation symptoms. These can include a rebound in anxiety or agitation. Insomnia is also commonly reported. Other potential symptoms include dizziness, nausea, and general flu-like symptoms such as body aches or malaise. Working closely with a doctor ensures a safer and more comfortable tapering process, managing any emergent symptoms effectively.